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Since the primary studies assessing the efficacy and safety of SGLT inhibitors as adjunct to insulin in people with type 1 diabetes were printed, it has been questioned whether the profit/threat ratio of these brokers in this indication may very well be optimised. Subsequently this study evaluated the benefit/risk of the SGLT2 inhibitor, dapagliflozin, in a specific sub-population of the general DEPICT population - i.e, in these with BMI ≥27 kg/m2. Right here, we current proof for the additional improved profit/danger ratio when using the SGLT2 inhibitor - dapagliflozin - in people with type 1 diabetes with BMI ≥27 kg/m2 and receiving intensive insulin therapy, based mostly on information accessible from the DEPICT trials. People with BMI ≥27 kg/m2 comprised over half of the participants in the general DEPICT study inhabitants. This pooled analysis confirmed comparable efficacy of dapagliflozin 5 mg in individuals with BMI ≥27 kg/m2 to that seen in the overall DEPICT population.